People who use MDMA usually take it as a capsule or tablet, though some swallow it in liquid form or snort the powder. The popular nickname Molly (slang for “molecular”) often refers to the supposedly “pure” crystalline powder form of MDMA, usually sold in capsules. However, people who purchase powder or capsules sold as Molly often actually get other drugs such as synthetic cathinones.
How does MDMA affect the brain?
MDMA increases the activity of three brain chemicals:
- Dopamine—causes a surge in euphoria and increased energy/activity
- Norepinephrine—increases heart rate and blood pressure, which are particularly risky for people with heart and blood vessel problems
- Serotonin—affects mood, appetite, sleep, and other functions. It also triggers hormones that affect sexual arousal and trust. The release of large amounts of serotonin likely causes the emotional closeness, elevated mood, and empathy felt by those who use MDMA.
Other health effects include:
- muscle cramping
- involuntary teeth clenching
- blurred vision
MDMA’s effects last about 3 to 6 hours, although many users take a second dose as the effects of the first dose begin to fade